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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49f650c7eb310e05c810722975a938b0753d496fbd583b2b3d5dd3f0b6995b8c' 
  AND token = 'eAe0lA0QAbzQfBt+eJN3ANJiLdk+ltoE8GguG4RZ4kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00121

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}