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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2581cc0cab8d948414e27fd7ba1034484d48552ffce0cf7d7749445a22723f45' 
  AND token = '3arA0gKUHHyPFAxV0EiODfKlR+yRDTDe0DcFKQcZffw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00089

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}