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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b1054ec425ba8b77cbd6a2927bcbabdb886a361e6899b666e7992a44198f1c' 
  AND token = 'yNTLskxIL9sLyy/R/KN8HKpe6Uel3RiCzG0KleiW60Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00087

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}