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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '868578f675b91835c5cde807ebe2508459fd8a0d8881d4c2f5bdc0a385fa6b58' 
  AND token = 'VMFDzwkEKsE/a0K/cZznQGBLMq3OhCQQdpvxtKYMysA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00110

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}