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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6498af0c4fbf66565e516368e22e2c97c70d195c3650995cf72f7c776e157c0' 
  AND token = 'r1sPjdzSJhnsQuVP6jaUsLLSVjujqnsaDJORhY+Z0p8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00101

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}