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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78003d79b392839a37a6aa106b1d1cbc489c6d7dd9014bb6b4afad742ee3c68' 
  AND token = 'sz529MNYeuoi2scYpYpAdpQo607egatOv9vqhBDW8fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}