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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5eb5e355a9404e077c93e3270d31ae5bec27d0072a45be97be0b05e10ddd3c8' 
  AND token = 'sIyd2dLgA1MQo3ccQ6R2hHgCfZI+5v7pGIKXPOH7Sqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00111

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}