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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645042895ebe646c6132f0206492e17af31980f3c20e8b8c75e6e9ed881ef05a' 
  AND token = '3THDYgaQK9U1ONgpEnoQnnUuHARKwFOQ9+2oW1ejrDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}