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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e4bc9d5806cdc366aa651a430cb6b7ee428eaa9e35160da921340fb53ce5184' 
  AND token = 'tagh5qbWasOiFalRWjQaXWbYkQHM+LatW3nOfclubKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00125

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}