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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b43351c62f1cfa66da29370f4f674c3f58a03addf936471cccc9e11772cd86aa' 
  AND token = 'QkMHbZCsdzBitGiVUzUzrDZOYY4rRPcdcF2Bom7514c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00088

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}