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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e48344168178d88588311b7f70ee10550c796b5dfeca9b781e0d7d60b41ac5a9' 
  AND token = 'Rj3vOJrdLl2vo8wB2bDHodbxurRqd2qDv38Rv+ncUbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}