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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '749a46dd4fac44112695d64eaed6e2e4d2767431b2140789d6b46b929c2b766c' 
  AND token = 'U6/tF3kemfVeIs1Ae4E/tCvjUO2Jwv+6Tod2sq2JW0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00090

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}