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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a222263162af98238e01fce4a10e20b6b262b6ea594e033e870d8ddee350763' 
  AND token = 'F2M0qdMJfOKseBj4dVg6eMqFNx+c39iYKXZUiEDwxFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00087

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}