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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '289ad35e35c2c6d2c30451e02f8155e78cb61254a159862c57329d1421c9a1a3' 
  AND token = 'zDZRsVHBs7viY/V6uxMIkPztL1f18TQGT6LjidZcWtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}