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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49391aad0cb2ad21eea2804bd78c2fa1746b983cd1c17b9f71321b195b8a9997' 
  AND token = 'Nfb+/PGnMFpeTxy6Tn8lWELgnmuHmHE9g5Irp1JYqJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00088

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}