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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c5a67ec5c42411f8bfd99c23fcf0b5c0e091f700ca7076c894f4bc04e49909' 
  AND token = 'oFSTSjchbj7D5CvtdQ8UE4YeuG1XWTOAla+7sAmdYRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00220

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}