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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb2e4b576af51f0fbe825cecb129e785df82d8be737f568c9f1c6daf711da56' 
  AND token = 'ugT2Cfu3YSLrA79snYsr8/I9q5iaY+DBBSufjZNOzRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}