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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cf80f1443bb7b16e8aac645569d54824a81043788ce3c81a4b442aa1865b611' 
  AND token = 'rIwzxQQV3BWF8tXChT5seecDbhYsFL4gxlpytulFgso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}