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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54380cedca119e69446e6b1efbe604c73fa9d5e9bd5ad29a1d02c0aef6feece4' 
  AND token = 'MXM9g6VjkatoBwOhL6+z/3nlpP3/Q3aOVWlSmJCfgCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}