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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '344899943d6e765b1ecd42a7e27f13b4a4b682ac607a733a80e886a159f727e5' 
  AND token = 'GYzbNY6wVRDZzfdE40LrsrRXno2WtBwiymWu9t9zb4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}