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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f0329d90242555fcaf5c5b44caf8a425dffd4a9ceda23260681b61aaf25d0ab' 
  AND token = 'T2hNQ+UTUPVi/4FH74VopE8UbBaVuOfkUbjIiKnYW4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}