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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a2d95d0d6d98a546f1f2db7ea331e17a868df37010783b2469df34dd0f529e' 
  AND token = 'tJx8RnVl1MHp0CCy7Y5FXRgxHC0ZUAXKc9HbCV+VVOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}