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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0a7ff3463dde2452d83642cc8abfb338f2b28af66617b23226229e1fc30777' 
  AND token = 'cfk59d9UqL7IlS6YF7dIB6SN6EdhNp0oBLLRD+5+TVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}